Molecular variation in tumour samples may relate to variation in clinical outcome. To facilitate such studies the Ontario Tumour Bank collects detailed information on every case.  The central data repository is updated nightly with current and de-identified information from the entire provincial collection.  The Ontario Tumour Bank can provide detailed information on over 400 clinical data elements. 

The database is structured to capture clinical details and progression of disease over the course of time, using disease site specific case report forms.  The following information is recorded for every case banked:

• Donor demographic information (e.g., age, sex, vital status);
• One or more clinical events, which document outcomes and progression of disease (e.g. initial diagnosis, metastasis, recurrence);
• Sample collection details (e.g., collection date, processing time);
• Pathology and diagnosis details (e.g. histology, size of tumour, grade);
• Staging;
• Patient history (e.g. prior cancers, weight loss, history of smoking);
• Family history of cancer;
• Treatment details for surgeries, radiotherapy and systemic therapy (e.g., start and end dates, intent, outcome, agents);
• Toxicities relating to treatment.